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Lidocaine enhances antitumor effects of sorafenib and GW5074 in colorectal cancer cells

Targeted therapies have broadened the treatment landscape for colorectal cancer (CRC), highlighting the need for rational combination strategies. Although sorafenib and GW5074 show therapeutic promise and lidocaine may sensitise cancer cells to treatment, the mechanisms underlying these combinations...

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Hlavní autoři: Tzu-Chiao Lin, Zih-Syuan Wu, Shih-Ming Huang, Che-Wei Liu, Je-Ming Hu, Chia-Cheng Wen
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis Group 2026-12-01
Edice:Journal of Enzyme Inhibition and Medicinal Chemistry
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On-line přístup:https://www.tandfonline.com/doi/10.1080/14756366.2026.2678755
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