Novel benzo chromene derivatives: design, synthesis, molecular docking, cell cycle arrest, and apoptosis induction in human acute myeloid leukemia HL-60 cells

A series of benzo[h]chromenes, benzo[f]chromenes, and benzo[h]chromeno[2,3-d]pyrimidines were prepared. All the newly synthesised compounds were selected by National Cancer Institute for single-dose testing against 60 cell lines. Benzo[h]chromenes 5a and 6a showed promising anti-cancer activity and...

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Principais autores:	Rania H. Abd El-Hameed, Mosaad S. Mohamed, Samir M. Awad, Bardes B. Hassan, Marwa Abd El-Fattah Khodair, Yara E. Mansour
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Taylor & Francis Group 2023-12-01
סדרה:	Journal of Enzyme Inhibition and Medicinal Chemistry
נושאים:	Benzocoumarin apoptosis cell cycle arrest AML HL-60
גישה מקוונת:	https://www.tandfonline.com/doi/10.1080/14756366.2022.2151592
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!