Co-crystallisation and humanisation of an anti-HER2 single-domain antibody as a theranostic tool.

Human epidermal growth factor receptor-2 (HER2) is a well-recognised biomarker associated with 25% of breast cancers. In most cases, early detection and/or treatment correlates with an increased chance of survival. This study, has identified and characterised a highly specific anti-HER2 single-domai...

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Autori principali:	Kovilen Sawmynaden, Nicholas Wong, Sarah Davies, Richard Cowan, Richard Brown, David Tang, Maud Henry, David Tickle, David Matthews, Mark Carr, Preeti Bakrania, Hong Hoi Ting, Gareth Hall
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Public Library of Science (PLoS) 2023-01-01
Serie:	PLoS ONE
Accesso online:	https://doi.org/10.1371/journal.pone.0288259
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