Fenfluramine increases survival and reduces markers of neurodegeneration in a mouse model of Dravet syndrome
Abstract Objective In patients with Dravet syndrome (DS), fenfluramine reduced convulsive seizure frequency and provided clinical benefit in nonseizure endpoints (e.g., executive function, survival). In zebrafish mutant scn1 DS models, chronic fenfluramine treatment preserved neuronal cytoarchitectu...
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| Principais autores: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Wiley
2024-02-01
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| coleção: | Epilepsia Open |
| Assuntos: | |
| Acesso em linha: | https://doi.org/10.1002/epi4.12873 |
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