The D113N mutation in the RING E3 ubiquitin protein ligase gene is not associated with ex vivo susceptibility to common anti-malarial drugs in African Plasmodium falciparum isolates

Abstract Background Plasmodium falciparum resistance to artemisinin-based combination therapy has emerged and spread in Southeast Asia. In areas where artemisinin resistance is emerging, the efficacy of combination is now based on partner drugs. In this context, the identification of novel markers o...

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Detalhes bibliográficos

Principais autores:	Mathieu Gendrot, Francis Tsombeng Foguim, Marie Gladys Robert, Rémy Amalvict, Joel Mosnier, Nicolas Benoit, Marylin Madamet, Bruno Pradines, the French National Reference Centre for Imported Malaria Study Group
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2018-03-01
coleção:	Malaria Journal
Assuntos:	Malaria Plasmodium falciparum Anti-malarial drug In vitro Resistance Molecular marker
Acesso em linha:	http://link.springer.com/article/10.1186/s12936-018-2252-2
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