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Small extracellular vesicles derived from cerebral endothelial cells with elevated microRNA 27a promote ischemic stroke recovery

Axonal remodeling is a critical aspect of ischemic brain repair processes and contributes to spontaneous functional recovery. Our previous in vitro study demonstrated that exosomes/small extracellular vesicles (sEVs) isolated from cerebral endothelial cells (CEC-sEVs) of ischemic brain promote axona...

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Principais autores: Yi Zhang, Zhongwu Liu, Michael Chopp, Michael Millman, Yanfeng Li, Pasquale Cepparulo, Amy Kemper, Chao Li, Li Zhang, Zheng Gang Zhang
Format: Artigo
Sprog:Inglês
Udgivet: Wolters Kluwer Medknow Publications 2025-03-01
Serier:Neural Regeneration Research
Fag:
axonal remodeling
cerebral endothelial cells
exosomes
mir-27a
mitochondria
semaphorin 6a
small extracellular vesicles
stroke
Online adgang:https://journals.lww.com/10.4103/NRR.NRR-D-22-01292
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