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Distinguishing functional from structural roles of conserved pore residues during formate translocation by the FocA anion channel

Abstract The formate‐specific anion channel FocA of Escherichia coli belongs to the superfamily of homopentameric formate‐nitrite transporters (FNT). Minimally nine amino acid residues are conserved in the formate translocation pore of each protomer of the pentamer, including a histidine (H209) and...

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Principais autores: Michelle Kammel, R. Gary Sawers
Format: Artigo
Sprog:Inglês
Udgivet: Wiley 2022-08-01
Serier:MicrobiologyOpen
Fag:
anion channel
conserved residues
FNT family
FocA
formate translocation
Online adgang:https://doi.org/10.1002/mbo3.1312
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