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Evaluating the prognostic significance of p53 and TP53 mutations in HPV-negative hypopharyngeal carcinoma patients: a 5-year follow-up retrospective study

Abstract Purpose To evaluate prognostic significance of human papillomavirus (HPV) in hypopharyngeal squamous cell carcinoma patients, and to investigate the effect of p53 and TP53 mutations on the prognosis of patients. Methods A total of 111 patients were enrolled in our retrospective study. HPV i...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Qiang Huang, Feiran Li, Mengyou Ji, Lan Lin, Chunyan Hu
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2023-04-01
Schriftenreihe:BMC Cancer
Schlagworte:
Human papillomavirus
TP53
Exon mutation
Hypopharyngeal squamous cell carcinoma patients
Non-disruptive mutation
Online-Zugang:https://doi.org/10.1186/s12885-023-10775-9
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