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A Novel N-Sulfonylamidine-Based Derivative Inhibits Proliferation, Migration, and Invasion in Human Colorectal Cancer Cells by Suppressing Wnt/β-Catenin Signaling Pathway

Wnt signaling has been implicated in the development and metastasis of colorectal cancer (CRC), as well as poorer outcomes. Thus, targeting the Wnt/β-catenin signaling pathway is expected to be a promising treatment option for the therapy of advanced metastatic CRC. A new N-sulfonylamidine derivativ...

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Principais autores: Xingming Zhao, Zhuo Han, Jiahui Ma, Shiqing Jiang, Xia Li
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2021-05-01
Serier:Pharmaceutics
Fag:
colorectal cancer
HCT-116 cells
26ag
EMT
Wnt/β-catenin
Online adgang:https://www.mdpi.com/1999-4923/13/5/651
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