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The spatiotemporal program of DNA replication is associated with specific combinations of chromatin marks in human cells.

The duplication of mammalian genomes is under the control of a spatiotemporal program that orchestrates the positioning and the timing of firing of replication origins. The molecular mechanisms coordinating the activation of about [Formula: see text] predicted origins remain poorly understood, partl...

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Hlavní autoři: Franck Picard, Jean-Charles Cadoret, Benjamin Audit, Alain Arneodo, Adriana Alberti, Christophe Battail, Laurent Duret, Marie-Noelle Prioleau
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2014-05-01
Edice:PLoS Genetics
On-line přístup:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1004282&type=printable
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