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Somatostatin regulates the clock sensitivity to evening light

Abstract Entrainment of the internal clock to the light–dark cycle is a fundamental feature of biological rhythms. Here, we show that animals genetically deficient for somatostatin (SST) are unable to respond normally to long photoperiodic conditions, showing a significantly delayed phase of activit...

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Hauptverfasser: Yoshiaki Yamaguchi, Satoru Masubuchi, Emi Kiyokage, Kazunori Toida, Yasutaka Mizoro, Toru Suzuki, Miho Sato, Jean-Michel Fustin, Keiko Tominaga, Hitoshi Okamura
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Portfolio 2025-11-01
Schriftenreihe:Scientific Reports
Online-Zugang:https://doi.org/10.1038/s41598-025-26904-2
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