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Structural organization of pregenomic RNA and the carboxy-terminal domain of the capsid protein of hepatitis B virus.

The Hepatitis B Virus (HBV) double-stranded DNA genome is reverse transcribed from its RNA pregenome (pgRNA) within the virus core (or capsid). Phosphorylation of the arginine-rich carboxy-terminal domain (CTD) of the HBV capsid protein (Cp183) is essential for pgRNA encapsidation and reverse transc...

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Bibliographic Details
Main Authors: Joseph C-Y Wang, Mary S Dhason, Adam Zlotnick
Format: Artigo
Language:Inglês
Published: Public Library of Science (PLoS) 2012-09-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23028319/pdf/?tool=EBI
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