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A pandemic influenza H1N1 live vaccine based on modified vaccinia Ankara is highly immunogenic and protects mice in active and passive immunizations.

BACKGROUND: The development of novel influenza vaccines inducing a broad immune response is an important objective. The aim of this study was to evaluate live vaccines which induce both strong humoral and cell-mediated immune responses against the novel human pandemic H1N1 influenza virus, and to sh...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Annett Hessel, Michael Schwendinger, Daniela Fritz, Sogue Coulibaly, Georg W Holzer, Nicolas Sabarth, Otfried Kistner, Walter Wodal, Astrid Kerschbaum, Helga Savidis-Dacho, Brian A Crowe, Thomas R Kreil, P Noel Barrett, Falko G Falkner
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2010-01-01
Schriftenreihe:PLoS ONE
Online-Zugang:http://europepmc.org/articles/PMC2922371?pdf=render
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