Citalopram exposure of hESCs during neuronal differentiation identifies dysregulated genes involved in neurodevelopment and depression

Selective serotonin reuptake inhibitors (SSRIs), including citalopram, are widely used antidepressants during pregnancy. However, the effects of prenatal exposure to citalopram on neurodevelopment remain poorly understood. We aimed to investigate the impact of citalopram exposure on early neuronal d...

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Autori principali:	Mari Spildrejorde, Magnus Leithaug, Athina Samara, Hans Christian D. Aass, Ankush Sharma, Ganesh Acharya, Hedvig Nordeng, Kristina Gervin, Robert Lyle
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2024-07-01
Serie:	Frontiers in Cell and Developmental Biology
Soggetti:	citalopram depression epigenetics neurodevelopment human embryonic stem cells single-cell RNA-seq
Accesso online:	https://www.frontiersin.org/articles/10.3389/fcell.2024.1428538/full
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