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Antiproliferative Activity of <i>Buddleja saligna</i> (Willd.) against Melanoma and <i>In Vivo</i> Modulation of Angiogenesis

Melanoma cells secrete pro-angiogenic factors, which stimulates growth, proliferation and metastasis, and therefore are key therapeutic targets. <i>Buddleja saligna</i> (BS), and an isolated triterpenoid mixture (DT-BS-01) showed a fifty percent inhibitory concentration (IC<sub>50</sub>) of 33.80 ±...

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Principais autores: Danielle Twilley, Velaphi C. Thipe, Navneet Kishore, Pierce Bloebaum, Catarina Roma-Rodrigues, Pedro V. Baptista, Alexandra R. Fernandes, Mamoalosi A. Selepe, Lenka Langhansova, Kattesh Katti, Namrita Lall
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2022-11-01
Serier:Pharmaceuticals
Fag:
<i>Buddleja saligna</i>
melanoma
antiproliferative activity
angiogenesis
ex ovo YSM
Online adgang:https://www.mdpi.com/1424-8247/15/12/1497
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