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Ferric citrate and apo-transferrin enable erythroblast maturation with β-globin from hemogenic endothelium

Abstract Red blood cell (RBC) generation from human pluripotent stem cells (PSCs) offers potential for innovative cell therapy in regenerative medicine as well as developmental studies. Ex vivo erythropoiesis from PSCs is currently limited by the low efficiency of functional RBCs with β-globin expre...

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Principais autores: Soo-Been Jeon, Hyebin Koh, A-Reum Han, Jieun Kim, Sunghun Lee, Jae-Ho Lee, Seung-Soon Im, Young-sup Yoon, Jong-Hee Lee, Ji Yoon Lee
Formato: Artigo
Idioma:Inglês
Publicado: Nature Portfolio 2023-08-01
Series:npj Regenerative Medicine
Acceso en liña:https://doi.org/10.1038/s41536-023-00320-4
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