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The Ferric uptake regulator (Fur) and iron availability control the production and maturation of the antibacterial peptide microcin E492.

Microcin E492 is a pore-forming bacteriocin with toxic activity against Enterobacteriaceae, which undergoes amyloid aggregation as a mechanism to regulate its toxicity. To be active, it requires the posttranslational attachment to the C-terminus of a glycosylated enterochelin derivative (salmochelin...

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Autors principals: Andrés E Marcoleta, Sergio Gutiérrez-Cortez, Felipe Hurtado, Yerko Argandoña, Gino Corsini, Octavio Monasterio, Rosalba Lagos
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2018-01-01
Col·lecció:PLoS ONE
Accés en línia:http://europepmc.org/articles/PMC6071977?pdf=render
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