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Anaplastic thyroid cancer cells reduce CD71 levels to increase iron overload tolerance

Abstract Background Follicular thyroid cancer (FTC) is a prevalent form of differentiated thyroid cancer, whereas anaplastic thyroid cancer (ATC) represents a rare, fast-growing, undifferentiated, and highly aggressive tumor, posing significant challenges for eradication. Ferroptosis, an iron-depend...

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Asıl Yazarlar: Simona D’Aprile, Simona Denaro, Anna Maria Pavone, Sebastiano Giallongo, Cesarina Giallongo, Alfio Distefano, Lucia Salvatorelli, Filippo Torrisi, Raffaella Giuffrida, Stefano Forte, Daniele Tibullo, Giovanni Li Volti, Gaetano Magro, Nunzio Vicario, Rosalba Parenti
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BMC 2023-11-01
Seri Bilgileri:Journal of Translational Medicine
Konular:
Thyroid cancer
CD71
Ferroptosis
Iron overload
Erastin
RSL3
Online Erişim:https://doi.org/10.1186/s12967-023-04664-9
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