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Post-Transcriptional Effects of miRNAs on PCSK7 Expression and Function: miR-125a-5p, miR-143-3p, and miR-409-3p as Negative Regulators

The regulatory mechanism of <i>PCSK7</i> gene is still unknown, although its encoded protein PC7 is the most ancient and highly conserved of all proprotein convertases and exhibits enzymatic and non-enzymatic functions in liver triglyceride regulation. Bioinformatics algorithms were used to predict...

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Principais autores: Mahshid Malakootian, Parisa Naeli, Seyed Javad Mowla, Nabil G. Seidah
פורמט: Artigo
שפה:Inglês
יצא לאור: MDPI AG 2022-06-01
סדרה:Metabolites
נושאים:
<i>PCSK7</i>
miR-125a-5p
miR-143-3p
miR-409-3p
RNA regulator
proprotein convertases
גישה מקוונת:https://www.mdpi.com/2218-1989/12/7/588
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