Synthesis of imidazo[1,2-a]pyridine-containing peptidomimetics by tandem of Groebke–Blackburn–Bienaymé and Ugi reactions

Peptidomimetics with a substituted imidazo[1,2-a]pyridine fragment were synthesized by a tandem of Groebke–Blackburn–Bienaymé and Ugi reactions. The target products contain substituted imidazo[1,2-a]pyridine and peptidomimetic moieties as pharmacophores with four diversity points introduced from rea...

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Principais autores:	Oleksandr V. Kolomiiets, Alexander V. Tsygankov, Maryna N. Kornet, Aleksander A. Brazhko, Vladimir I. Musatov, Valentyn A. Chebanov
Format:	Artigo
Jezik:	Inglês
Izdano:	Beilstein-Institut 2023-05-01
Serija:	Beilstein Journal of Organic Chemistry
Teme:	groebke–blackburn–bienaymé reaction imidazo[1,2-a]pyridine isocyanide multicomponent reaction peptidomimetic ugi reaction
Online dostop:	https://doi.org/10.3762/bjoc.19.53
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