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CLAMP and Zelda function together to promote Drosophila zygotic genome activation

During the essential and conserved process of zygotic genome activation (ZGA), chromatin accessibility must increase to promote transcription. Drosophila is a well-established model for defining mechanisms that drive ZGA. Zelda (ZLD) is a key pioneer transcription factor (TF) that promotes ZGA in th...

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Furkejuvvon:
Váldodahkkit: Jingyue Duan, Leila Rieder, Megan M Colonnetta, Annie Huang, Mary Mckenney, Scott Watters, Girish Deshpande, William Jordan, Nicolas Fawzi, Erica Larschan
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: eLife Sciences Publications Ltd 2021-08-01
Ráidu:eLife
Fáttát:
zygotic genome activation
CLAMP
Zelda
Drosophila embryo
pioneer TF
Liŋkkat:https://elifesciences.org/articles/69937
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