Oligopeptide Targeting Sortase A as Potential Anti-infective Therapy for Staphylococcus aureus
Sortase A (SrtA)-catalyzed anchorage of surface proteins in most Gram-positive bacteria is indispensable for their virulence, suggesting that this transpeptidase is a promising target for antivirulence therapy. Here, an oligopeptide, LPRDA, was identified as an effective inhibitor of SrtA via virtua...
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| Principais autores: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2018-02-01
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| coleção: | Frontiers in Microbiology |
| Assuntos: | |
| Acesso em linha: | http://journal.frontiersin.org/article/10.3389/fmicb.2018.00245/full |
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