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Omega 3 fatty acid docosahexaenoic acid (DHA) mitigates inflammatory responses in experimental sepsis

BackgroundSepsis is a life-threatening condition characterized by organ dysfunction resulting from a dysregulated host response to infection. Sepsis induces systemic inflammation and increases adhesion molecule expression and activation, promoting leukocyte adhesion to the endothelium. In addition,...

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Autori principali: Bianca Portugal Tavares de Moraes, Isabelle Moraes-de-Souza, Gabrielle Lacerda de Souza Gomes-Reis, Marina Ferreira-Costa, Carolina Medina Coeli da Cunha, Matheus Augusto Patrício de Almeida, Vanessa Estato, Kauê Francisco Corrêa Souza e Souza, Francisco da Silva dos Santos, Maria Alice dos Santos Mascarenhas Brito, Patrícia Novaes Soares, Wilza Arantes Ferreira Peres, Roland Immler, Matteo Napoli, Patrícia Torres Bozza, Hugo Caire de Castro-Faria-Neto, Markus Sperandio, Adriana Ribeiro Silva, Cassiano Felippe Gonçalves-de-Albuquerque
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2025-11-01
Serie:Frontiers in Pharmacology
Soggetti:
docosahexaenoic acid
omega 3
microcirculation
neuroinflammation
intravital microscopy
neutrophils
Accesso online:https://www.frontiersin.org/articles/10.3389/fphar.2025.1708348/full
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