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Interplay of gene expression noise and ultrasensitive dynamics affects bacterial operon organization.

Bacterial chromosomes are organized into polycistronic cotranscribed operons, but the evolutionary pressures maintaining them are unclear. We hypothesized that operons alter gene expression noise characteristics, resulting in selection for or against maintaining operons depending on network architec...

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Détails bibliographiques
Auteurs principaux: J Christian J Ray, Oleg A Igoshin
Format: Artigo
Langue:Inglês
Publié: Public Library of Science (PLoS) 2012-01-01
Collection:PLoS Computational Biology
Accès en ligne:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1002672&type=printable
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