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Comparative pharmacokinetics for bioequivalence of pramipexole dihydrochloride extended-release tablets in fasting and fed Chinese healthy volunteers: a randomized, open-label, single-dose, crossover study

Abstract Background We aimed to compare pharmacokinetic (PK) profiles and establish bioequivalence between generic and original pramipexole extended-release (ER) tablets in healthy Chinese volunteers under fasting and fed conditions. Methods This investigation consisted of two randomized, open-label...

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Principais autores: Qian Chen, Hui-qing Shi, Yi-fang Chen, Wei Zhang, Lan Ye, Ya-ming Li, Ting-ting Hu
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2026-05-01
coleção:BMC Pharmacology and Toxicology
Assuntos:
Pramipexole
Bioequivalence
Pharmacokinetics
Safety
Tolerability
Acesso em linha:https://doi.org/10.1186/s40360-026-01144-w
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