Defining the CD39/CD73 Axis in SARS-CoV-2 Infection: The CD73^- Phenotype Identifies Polyfunctional Cytotoxic Lymphocytes

The ectonucleotidases CD39 and CD73 regulate immune responses by balancing extracellular ATP and adenosine in inflammation and are likely to be involved in the pathophysiology of COVID-19. Here, we analyzed CD39 and CD73 on different lymphocyte populations in a small cohort of COVID-19 patients and...

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Autori principali:	Parimah Ahmadi, Philip Hartjen, Matin Kohsar, Silke Kummer, Stefan Schmiedel, Jan-Hendrik Bockmann, Anahita Fathi, Samuel Huber, Friedrich Haag, Julian Schulze zur Wiesch
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2020-07-01
Serie:	Cells
Soggetti:	COVID-19 purinergic signaling CD73 CD39 cytotoxic lymphocytes granzyme B
Accesso online:	https://www.mdpi.com/2073-4409/9/8/1750
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