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TAL1 overexpression in induced pluripotent stem cells promotes the formation of hematopoietic cell-forming complexes but inhibits enucleation in vitro

The in vitro generation of human red blood cells (RBCs) from stem cells, such as induced pluripotent stem cells (iPSCs), holds promise for transfusable RBCs but faces challenges, including RBC maturation, enucleation, and large-scale production. In this study, we evaluated the effect of conditional...

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主要な著者: Arim Shin, Sung Ah Park, Ji Yeon Kim, Eun Jung Baek
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2025-04-01
シリーズ:Frontiers in Cell and Developmental Biology
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オンライン・アクセス:https://www.frontiersin.org/articles/10.3389/fcell.2025.1474631/full
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