Avapritinib reduces symptoms and mast cell burden in systemic mastocytosis
Abstract Background Mastocytosis is driven by a clonal expansion of mast cells, commonly triggered by the KIT D816V mutation which is present in over 90% of adult patients. Individuals with indolent systemic mastocytosis (ISM) frequently experience recurrent anaphylaxis and mast cell mediator-relate...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
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BMC
2025-09-01
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| Schriftenreihe: | Allergy, Asthma & Clinical Immunology |
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| Online-Zugang: | https://doi.org/10.1186/s13223-025-00986-z |
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