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Phase-dependent efficacy of intravenous amniotic mesenchymal stem cells in a rat spinal cord injury model

Abstract Background Spinal cord injury results in profound neurological disability driven initially by primary mechanical damage and subsequently by secondary injury processes characterized by progressive neuroinflammation. Intravenous administration of human amniotic mesenchymal stem cells (MSC) ha...

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Principais autores: Yi Qi, Masahito Kawabori, Sho Yamaguchi, Yo Nakahara, Zheng Li, Sumio Ohtsuki, Miki Fujimura
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2026-04-01
coleção:Stem Cell Research & Therapy
Assuntos:
Spinal cord injury
Amniotic mesenchymal stem cells
Intravenous administration
Therapeutic window
Neuroinflammation
Neutrophils
Acesso em linha:https://doi.org/10.1186/s13287-026-05018-0
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