Hypothalamic Irak4 is a genetically controlled regulator of hypoglycemia-induced glucagon secretion

Objectives: Glucagon secretion to stimulate hepatic glucose production is the first line of defense against hypoglycemia. This response is triggered by so far incompletely characterized central hypoglycemia-sensing mechanisms, which control autonomous nervous activity and hormone secretion. The obje...

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Principais autores:	Alexandre Picard, Xavier Berney, Judit Castillo-Armengol, David Tarussio, Maxime Jan, Ana Rodriguez Sanchez-Archidona, Sophie Croizier, Bernard Thorens
Formato:	Artigo
Idioma:	Inglês
Publicado:	Elsevier 2022-07-01
Series:	Molecular Metabolism
Assuntos:	Genetic screening Insulin-induced hypoglycemia Hypothalamus Glucagon Autonomous nervous system
Acceso en liña:	http://www.sciencedirect.com/science/article/pii/S2212877822000485
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