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Increased Responsiveness to Toll-Like Receptor 4 Stimulation in Peripheral Blood Mononuclear Cells from Patients with Recent Onset Rheumatoid Arthritis

Background. Cell signaling via Toll-like receptors (TLRs) leads to synovial inflammation in rheumatoid arthritis (RA). We aimed to assess effects of TLR2 and TLR4 stimulation on proinflammatory cytokine production by peripheral blood mononuclear cells (PBMCs) from patients with recent-onset RA, oste...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: M. L. Kowalski, A. Wolska, J. Grzegorczyk, J. Hilt, M. Jarzebska, M. Drobniewski, M. Synder, M. Kurowski
Format: Artigo
Sprache:Inglês
Veröffentlicht: Wiley 2008-01-01
Schriftenreihe:Mediators of Inflammation
Online-Zugang:http://dx.doi.org/10.1155/2008/132732
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