Quantitative fragmentomics allow affinity mapping of interactomes

Protein networks have been widely explored but most binding affinities remain unknown, limiting the quantitative interpretation of interactomes. Here the authors measure affinities of 65,000 interactions involving human PDZ domains and target sequence motifs relevant for viral infection and cancer.

书目详细资料

Principais autores:	Gergo Gogl, Boglarka Zambo, Camille Kostmann, Alexandra Cousido-Siah, Bastien Morlet, Fabien Durbesson, Luc Negroni, Pascal Eberling, Pau Jané, Yves Nominé, Andras Zeke, Søren Østergaard, Élodie Monsellier, Renaud Vincentelli, Gilles Travé
格式:	Artigo
语言:	Inglês
出版:	Nature Portfolio 2022-09-01
丛编:	Nature Communications
在线阅读:	https://doi.org/10.1038/s41467-022-33018-0
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