The effects of mitochondrial dysfunction on energy metabolism switch by HIF-1α signalling in granulosa cells of polycystic ovary syndrome

BACKGROUND: This study aimed to determine the effects of mitochondrial dysfunction on energy metabolism of granulosa cells (GCs) and the competence of oocytes in polycystic ovary syndrome (PCOS). MATERIAL AND METHODS: A total of 107 patients who underwent controlled ovarian hyperstimulation (COH) we...

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Bibliografische Detailangaben

Hauptverfasser:	Jing Wang, Xiaohua Wu
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Via Medica 2020-04-01
Schriftenreihe:	Endokrynologia Polska
Schlagworte:	polycystic ovary syndrome granulosa cells glycolysis mitochondrial functions hypoxia inducible factor 1α
Online-Zugang:	https://journals.viamedica.pl/endokrynologia_polska/article/view/66473
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