Variants of IL6, IL10, FCN2, RNASE3, IL12B and IL17B loci are associated with Schistosoma mansoni worm burden in the Albert Nile region of Uganda.

<h4>Background</h4>Individuals genetically susceptible to high schistosomiasis worm burden may contribute disproportionately to transmission and could be prioritized for control. Identifying genes involved may guide development of therapy.<h4>Methodology/principal findings</h4>A cohort of 606 childr...

Fuld beskrivelse

Bibliografiske detaljer

Principais autores:	Oscar Asanya Nyangiri, Julius Mulindwa, Joyce Namulondo, Anna Kitibwa, Jacent Nassuuna, Alison Elliott, Magambo Phillip Kimuda, Alex Boobo, Barbara Nerima, Moses Adriko, Nathan J Dunton, Gaganjit Kaur Madhan, Mark Kristiansen, Miriam Casacuberta-Partal, Harry Noyes, Enock Matovu, TrypanoGEN+ Research group of the H3Africa consortium
Format:	Artigo
Sprog:	Inglês
Udgivet:	Public Library of Science (PLoS) 2023-11-01
Serier:	PLoS Neglected Tropical Diseases
Online adgang:	https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0011796&type=printable
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