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Structural insights into the mechanism of phosphoregulation of the retinoblastoma protein.

The retinoblastoma susceptibility protein RB1 is a key regulator of cell proliferation and fate. RB1 operates through nucleating the formation of multi-component protein complexes involved in the regulation of gene transcription, chromatin structure and protein stability. Phosphorylation of RB1 by c...

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Principais autores: Ekaterina P Lamber, Fabienne Beuron, Edward P Morris, Dmitri I Svergun, Sibylle Mittnacht
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science (PLoS) 2013-01-01
סדרה:PLoS ONE
גישה מקוונת:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0058463&type=printable
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