Circulating metabolic biomarkers mediated causal relationship between gut microbiota and bladder cancer: a two-step mendelian randomization study

Abstract Background Dysbiosis of the gut microbiota (GM) has been reported to be associated with cancers, including bladder cancer (BLCA). However, the specific causal relationship between GM and BLCA, as well as the mediating role of circulating metabolic biomarkers (CMBs), has remained unclear. Th...

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Principais autores:	Fa-Ye Wei, Qi-Huan He, Bin-Tong Yin, Jia-Wen Zhao, Yu-Tong Zhao, Zheng-Shu Wei, Yu-Jian Li, Hai-Qi Liang, Min Qin, Ji-Wen Cheng
Format:	Artigo
Sprog:	Inglês
Udgivet:	Springer 2025-05-01
Serier:	Discover Oncology
Fag:	Gut microbiota Circulating metabolic biomarkers Bladder cancer Mendelian randomization TSMR
Online adgang:	https://doi.org/10.1007/s12672-025-02618-9
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