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Toward alpha‐synuclein seed amplification assay in clinical practice

Abstract INTRODUCTION Seed amplification assays (SAAs) demonstrate remarkable diagnostic performance in alpha‐synucleinopathies. However, existing protocols lack accessibility in routine laboratories, mainly due to the requirement for in‐house production of recombinant alpha‐synuclein (aSyn). This s...

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Asıl Yazarlar: Mathieu Verdurand, Flora Kaczorowski, Sophie Dautricourt, Virginie Desestret, Maïté Formaglio, Hélène Mollion, Gil Petitnicolas, Ali Afifi, Anthony Fourier, Antoine Garnier‐Crussard, Isabelle Quadrio
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Wiley 2025-01-01
Seri Bilgileri:Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
Konular:
alpha‐synuclein (α‐synuclein)
aSyn
biomarker
brain homogenate (BH)
cerebrospinal fluid (CSF)
dementia with Lewy bodies (DLB)
Online Erişim:https://doi.org/10.1002/dad2.70066
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