Differentiation and transplantation of human induced pluripotent stem cell-derived otic epithelial progenitors in mouse cochlea

Abstract Background Inner ear hair cells as mechanoreceptors are extremely important for hearing. Defects in hair cells are a major cause of deafness. Induced pluripotent stem cells (iPSCs) are promising for regenerating inner ear hair cells and treating hearing loss. Here, we investigated migration...

Descrizione completa

Dettagli Bibliografici

Autori principali:	Jianling Chen, Fanfan Hong, Cui Zhang, Liang Li, Cuicui Wang, Haosong Shi, Yong Fu, Jinfu Wang
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2018-08-01
Serie:	Stem Cell Research & Therapy
Soggetti:	Sensorineural hearing loss Induced pluripotent stem cells Hair cell-like cells Otic epithelial progenitors Synaptic connection
Accesso online:	http://link.springer.com/article/10.1186/s13287-018-0967-1
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!