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Large-Scale Structure-Based Prediction of Stable Peptide Binding to Class I HLAs Using Random Forests

Prediction of stable peptide binding to Class I HLAs is an important component for designing immunotherapies. While the best performing predictors are based on machine learning algorithms trained on peptide-HLA (pHLA) sequences, the use of structure for training predictors deserves further explorati...

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Autors principals: Jayvee R. Abella, Dinler A. Antunes, Cecilia Clementi, Lydia E. Kavraki
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020-07-01
Col·lecció:Frontiers in Immunology
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Accés en línia:https://www.frontiersin.org/article/10.3389/fimmu.2020.01583/full
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