BLIMP-1 Mediated Downregulation of TAK1 and p53 Molecules Is Crucial in the Pathogenesis of Kala-Azar

Precise regulation of inflammasome is critical during any pathogenic encounter. The whole innate immune system comprising of pattern recognition receptors (PRRs) relies on its ability to sense microbes. The fate of cellular death in infected cells depends mostly on the activation of these inflammaso...

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Hlavní autoři:	Gundappa Saha, Adarsh Kumar Chiranjivi, Bakulesh M. Khamar, Kumari Prerna, Manish Kumar, Vikash Kumar Dubey
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2020-10-01
Edice:	Frontiers in Cellular and Infection Microbiology
Témata:	Leishmaniasis kala-azar immuno-suppression BLIMP-1 macrophage
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fcimb.2020.594431/full
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