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New comorbidity index associated with survival after chimeric antigen receptor T-cell therapy for large B-cell lymphoma

Abstract: The cumulative impact of baseline comorbidities on outcomes of chimeric antigen receptor T-cell (CAR-T) therapy is not well established. Therefore, we developed and validated a Cellular Therapy Comorbidity Index (CT-CI) to predict outcomes following CD19-directed CAR-T therapy for large B-...

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Principais autores: Uri Greenbaum, Hamza Hashmi, Mahmoud Elsawy, Soyoung Kim, Amy Moskop, Temitope Oloyede, Farrukh T. Awan, Veronika Bachanova, Talha Badar, Merav Bar, Pere Barba, Amer M. Beitinjaneh, Amanda Cashen, Bhagirathbhai Dholaria, Umar Farooq, Jessica Foglesong, Siddhartha Ganguly, Peiman Hematti, LaQuisa C. Hill, Michael D. Jain, Tania Jain, Partow Kebriaei, Adam S. Kittai, Frederick L. Locke, Premal D. Lulla, Joseph P. McGuirk, Elena Mead, Alberto Mussetti, Taiga Nishihori, Amanda L. Olson, Martina Pennisi, Miguel-Angel Perales, Praveen Ramakrishnan Geethakumari, Peter A. Riedell, Wael Saber, Roni Shouval, Elizabeth J. Shpall, Margarida Magalhaes-Silverman, Christopher Strouse, Cameron J. Turtle, Anusha Vallurupalli, Kitsada Wudhikarn, Marcelo C. Pasquini, Sairah Ahmed, Mohamed Sorror
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2026-01-01
Serija:Blood Advances
Online dostop:http://www.sciencedirect.com/science/article/pii/S2473952925004902
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