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Heat shock proteins (Hsp70 and Hsp90) in neurodegeneration: pathogenic roles and therapeutic potential

The maintenance of protein homeostasis is essential for neuronal survival and function; however, it progressively declines with age, predisposing the brain to neurodegenerative diseases. Molecular chaperones Hsp70 and Hsp90 are key guardians of proteostasis, pivotally regulating protein folding, ref...

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Hlavní autor: Noureddine Ben Khalaf
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2026-02-01
Edice:Frontiers in Aging Neuroscience
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On-line přístup:https://www.frontiersin.org/articles/10.3389/fnagi.2026.1711422/full
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