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Targeting SAA expression via siRNA mitigates preterm birth induced by maternal inflammation

IntroductionPlacental inflammation is a major contributor to preterm birth (PTB), and there are currently few targeted strategies to prevent PTB and its associated adverse neonatal outcomes. Serum amyloid A (SAA), particularly the isoforms SAA1 and SAA2, are well-recognized inflammatory markers, but...

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Príomhchruthaitheoirí: Jun Lei, Yang Liu, Jin Liu, Anguo Liu, Kimberly Jones-Beatty, Elizabeth Ann L. Enninga, Courtney Townsel, Irina Burd
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Frontiers Media S.A. 2026-01-01
Sraith:Frontiers in Pharmacology
Ábhair:
Rochtain ar líne:https://www.frontiersin.org/articles/10.3389/fphar.2026.1749966/full
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