G-protein coupled receptor solubilization and purification for biophysical analysis and functional studies, in the total absence of detergent

G-protein coupled receptors (GPCRs) constitute the largest class of membrane proteins and are a major drug target. A serious obstacle to studying GPCR structure/function characteristics is the requirement to extract the receptors from their native environment in the plasma membrane, coupled with the...

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מידע ביבליוגרפי

Principais autores:	Mohammed Jamshad, Jack Charlton, Yu‑Pin Lin, Sarah J. Routledge, Zharain Bawa, Timothy J. Knowles, Michael Overduin, Niek Dekker, Tim R. Dafforn, Roslyn M. Bill, David R. Poyner, Mark Wheatley
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Portland Press 2015-04-01
סדרה:	Bioscience Reports
נושאים:	adenosine receptor detergent-free G-protein coupled receptor (GPCR) protein thermostability structure
גישה מקוונת:	http://www.bioscirep.org/bsr/035/e188/bsr035e188.htm
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