Ginsenoside CK targets PHD2 to prevent platelet adhesion and enhance blood circulation by modifying the three-dimensional arrangement of collagen

Platelets are indispensable for physiological hemostasis and pathological thrombus formation, and platelet adhesion to endothelial collagen is a critical initial step in thrombus formation, often overlooked in current antiplatelet therapies. This study aims to elucidate how ginsenoside CK enhances h...

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Autors principals:	Chuanjing Cheng, Kaixin Liu, Jinling Zhang, Yanqi Han, Tiejun Zhang, Yuanyuan Hou, Gang Bai
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2025-03-01
Col·lecció:	Acta Pharmaceutica Sinica B
Matèries:	PHD2 Platelet adhesion Collagen PHD2 inhibitor Ginsenoside CK Blood circulation
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S2211383524004957
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