Etomidate-Induced myoclonus in Sprague‒Dawley rats involves the activation of neocortical Calpain-2 and its decrement on KCC2 protein
Abstract Background Etomidate-induced myoclonus has become a pressing clinical problem with an incidence of 50–80%. The underlying mechanism involves neocortical glutamate accumulation and N-methyl-d-aspartate (NMDA) receptor activity. However, the therapeutic target remains uncertain. Methods Adult...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BMC
2025-04-01
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| Col·lecció: | BMC Anesthesiology |
| Matèries: | |
| Accés en línia: | https://doi.org/10.1186/s12871-025-03065-3 |
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