Inflammatory mediators differentially regulate megakaryopoiesis and thrombopoiesis in myelofibrosis and essential thrombocythemia

Abstract Chronic myeloproliferative neoplasms are characterized by clonal myeloid expansion driven by activating mutations in the JAK2 pathway and chronic inflammation. The aim was to investigate the contribution of circulating inflammatory mediators to the abnormalities in the megakaryocytic lineag...

Descrizione completa

Dettagli Bibliografici

Autori principali:	Danila B. Yañuk, Adela S. Cellucci, Rosana F. Marta, Ailen D. Discianni Lupi, Geraldine De Luca, Ana C. Glembotsky, Miguel A. Castro Rios, Beatriz Moiraghi, Federico Sackmann, Verónica Cortes Guerrieri, Paula G. Heller, Nora P. Goette, Paola Roxana Lev
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Portfolio 2025-12-01
Serie:	Scientific Reports
Accesso online:	https://doi.org/10.1038/s41598-025-27594-6
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!