SIRT1 modulates microglia phenotypes via inhibiting drp1 phosphorylation reduces neuroinflammation in heatstroke

Background: Brain injury often results in high mortality rates and significant sequelae following severe heatstroke (HS). Neuroinflammation aggravates HS-induced brain injury, yet the involvement of microglia in heat-induced neuroinflammation deserves further investigation. Methods: Our study invest...

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Detalhes bibliográficos

Principais autores:	Jie Zhu, Panshi Jin, Tingting Zhou, Dingshun Zhang, Zixin Wang, Zhen Tang, Zhifeng Liu, Guangli Ren
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2024-11-01
coleção:	Brain Research Bulletin
Assuntos:	Heatstroke SIRT1 Microglia Neuroinflammation Mitochondrial quality control
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S0361923024002351
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