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Neutrophil Cathepsin G, but Not Elastase, Induces Aggregation of MCF-7 Mammary Carcinoma Cells by a Protease Activity-Dependent Cell-Oriented Mechanism

We previously found that a neutrophil serine protease, cathepsin G, weakens adherence to culture substrates and induces E-cadherin-dependent aggregation of MCF-7 human breast cancer cells through its protease activity. In this study, we examined whether aggregation is caused by degradation of adhesi...

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Auteurs principaux: Satoru Yui, Yuuki Osawa, Takeo Ichisugi, Riyo Morimoto-Kamata
Format: Artigo
Langue:Inglês
Publié: Wiley 2014-01-01
Collection:Mediators of Inflammation
Accès en ligne:http://dx.doi.org/10.1155/2014/971409
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