R-etodolac is a more potent Wnt signaling inhibitor than enantiomer, S-etodolac

Etodolac is an FDA-approved nonsteroidal anti-inflammatory drug (NSAID) used to treat a variety of inflammatory diseases. The drug is administered as a racemate (50/50 mixture of R- and S- enantiomers), however, studies have shown that the two enantiomers have distinct biologic and pharmacokinetic d...

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Auteurs principaux:	JoAnn S. Roberts, Chao Ma, Sarah Y.T. Robertson, Stephen Kang, Christiana S. Han, Sophie X. Deng, Jie J. Zheng
Format:	Artigo
Langue:	Inglês
Publié:	Elsevier 2022-07-01
Collection:	Biochemistry and Biophysics Reports
Sujets:	Wnt signaling R-etodolac S-etodolac Limbal stem epithelial cells
Accès en ligne:	http://www.sciencedirect.com/science/article/pii/S2405580822000322
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